Textbook: Smith 3rd Ed. (2010)

Chapter 24: Carbonyl Condensation Reactions

Practice Problems (No matching mendel sets were found.)

Individual Problems

Problem # 743

Enolates are nucleophiles and react with a variety of electrophiles.

Carbonyls are electrophiles. But aldehydes/ketones and  esters/acid chlorides often form different products.


Use curved arrows to draw a mechanism for each reaction below. How do the two products differ?

Problem # 749

Show how to prepare each compound below from propanal. I've marked the "cuts" for you.

Problem # 746

Show what combination of aldehyde, ketone, and/or ester can prepare each compound below. Every compound is a Claisen or aldol product.

Problem # 747

Show a combination of enolate (nucleophile) and electrophile that can produce each compound below.

Remember that all enolates come from carbonyls.

Problem # 750

Let's work through a Robinson annulation.

Work backwords to determine the starting materials needed to produce each intermediate below, then show a mechanism for the overall reaction.