MS 908 - SN1-SN2-E1-E2 Review Submitted by Matt on August 6, 2011.

Textbook and Chapter: Carey and Giuliano 8th Ed. (2010), Chapter 8

Keywords: leaving groups, nucleophilicity, SN1/SN2/E1/E2

Description: Goes through substitution and elimination competition reactions:

  • Nucleophile strength trends
  • Leaving group trends
  • Steric effects
  • How to tell the difference between SN1, SN2, E1, and E2 reaction conditions

Total Problems: 10

Problem # 703

Show two ways to prepare the ether below from a combination of an alcohol and an alkyl halide via the Williamson ether synthesis.

Is one way better than the other? Why?

Problem # 560

For each reaction below, determine whether the primary reaction is SN1, SN2, E1, or E2, and then draw the product.

Note: Me = methyl (CH3)